Synthesis and Isolation of Impurities

• Synthesis, Isolation and purification of the pharmaceutical impurity.
• Structure Interpretation - Characterizations of unknown molecules using HPLC, LCMS, NMR, techniques.

Lab is equipped with THE INSTRUMENT:

• MICROWAVE SYNTHESISZER (CEM DISCOVER).
• FLASH CHROMATOGRAPHY SYSTEM WITH PDA & ELSD DETECTOR
• LYOPHILIZERS
• ROTAVAPOURS
• PREP HPLCS WITH PDA.
• LCMS SYSTEMS.

We engaged in dealing with impurities and deuterium labelled compounds having applications in various industry segments such as Pharmaceuticals, Bio-Pharmaceuticals, etc.

Our work profile can be broadly categorized as follows

• Synthesis of impurities, metabolites, labelled drugs (isotopomers) with combination of multi-step synthesis and purification techniques (preparative and flash chromatography).
• Isolation and purification of known and unknown impurities (especially impurities formed due to side reaction in synthesis and formulation processes, stability studies, forced degradation and leachable extractable study).
• Structure interpretation of unknown impurities by spectral analysis.

Till date we have synthesized about 500+ pharmacopeial / non pharmacopeial impurities. Click here to Know More