Synthesis and Isolation of Impurities
- Synthesis, Isolation and purification of the pharmaceutical impurity.
- Structure Interpretation - Characterizations of unknown molecules using HPLC, LCMS, NMR, techniques.
Lab is equipped with THE INSTRUMENT:
- MICROWAVE SYNTHESISZER (CEM DISCOVER).
- FLASH CHROMATOGRAPHY SYSTEM WITH PDA & ELSD DETECTOR
- PREP HPLCS WITH PDA.
- LCMS SYSTEMS.
We engaged in dealing with impurities and deuterium labelled compounds having applications in various industry segments such as Pharmaceuticals, Bio-Pharmaceuticals, etc.
Our work profile can be broadly categorized as follows
- Synthesis of impurities, metabolites, labelled drugs (isotopomers) with combination of multi-step synthesis and purification techniques (preparative and flash chromatography).
- Isolation and purification of known and unknown impurities (especially impurities formed due to side reaction in synthesis and formulation processes, stability studies, forced degradation and leachable extractable study).
- Structure interpretation of unknown impurities by spectral analysis.
Till date we have synthesized about 500+ pharmacopeial / non pharmacopeial impurities. Click here to Know More